What Doct
ors Think


Survey Results
Are SSRI antidepressants effective?
1. How many years have you been practicing psychiatry?
 Response
Percent
Response
Count
1-5
2.2%1
6-10
13.0%6
11-20
26.1%12
21-30
34.8%16
More than 30
23.9%11
 answered question46
 
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0
2. Which is your preferred selective serotonin reuptake inhibitor (SSRIs) drug for treating patients with depression? Please pick only one.
 Response
Percent
Response
Count
citalopram (Celexa, Cipramil, Emocal, Sepram, Seropram)
15.6%7
escitalopram oxalate (Lexapro, Cipralex, Esertia)
33.3%15
fluoxetine (Prozac, Fontex, Seromex, Seronil, Sarafem, Fluctin (EUR), Fluox (NZ))
17.8%8
fluvoxamine maleate (Luvox, Faverin) 0.0%0
paroxetine (Paxil, Seroxat, Aropax, Deroxat, Rexetin, Xetanor, Paroxat)
2.2%1
sertraline (Zoloft, Lustral, Serlain)
20.0%9
dapoxetine 0.0%0
duloxetine hydrochloride (Cymbalta)
11.1%5
 answered question45
 
skipped question
1
3. Do you use SSRI drugs for off-label indications?
 Response
Percent
Response
Count
Yes
71.7%33
No
28.3%13
view commentOther (please specify)2
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0
4. Are the majority of your SSRI drug prescriptions for
 Response
Percent
Response
Count
On-label use of the drugs as defined by the FDA.
97.8%44
Off-label use of the drugs.
2.2%1
view commentOther (please specify)1
 answered question45
 
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1
5. A study, "Initial Severity and Antidepressant Benefits: A Meta-Analysis of Data Submitted to the Food and Drug Administration," published in the most recent issue of the "PLoS Medicine" journal, http://medicine.plosjournals.org/perlserv/?request=get-document&doi=10.1371/journal.pmed.0050045 concluded that "... compared with placebo, the new-generation antidepressants do not produce clinically significant improvements in depression in patients who initially have moderate or even very severe depression, but show significant effects only in the most severely depressed patients."Based on your experience with your patients who are on SSRI drugs, do you agree or disgaree with this article's conclusion?
 Response
Percent
Response
Count
I AGREE with this study's conclusion.
13.0%6
I DISAGREE with this study's conclusion.
87.0%40
view commentOther (please specify)3
 answered question46
 
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0
6. What will you do as a result of reviewing this study?
 Response
Percent
Response
Count
Increase usage of SSRI drugs. 0.0%0
Decrease usage of SSRI drugs.
2.2%1
This study will not affect my usage of SSRI drugs.
97.8%44
view commentOther (please specify)2
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1
7. The results of this study will be submitted to the FDA. What action do you think the FDA should take based on this study?
 Response
Percent
Response
Count
Restrict SSRI on-label use for only "severe" depression.
2.2%1
Take no action based on this study.
50.0%23
Do additional studies.
56.5%26
view commentOther (please specify)4
 answered question46
 
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0
8. If the FDA imposes additional restrictions for prescribing SSRI drugs as a result of this study, will that affect how you prescribe these drugs?
 Response
Percent
Response
Count
Yes
32.6%14
No
67.4%29
view commentOther (please specify)4
 answered question43
 
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3
9. Global sales of antidepressants were approximately $21 billion in 2007. How do you think this study will affect SSRI drug sales?
 Response
Percent
Response
Count
Will INCREASE sales. 0.0%0
Will DECREASE sales.
50.0%23
Will have no significant impact on sales.
50.0%23
Other (please specify)0
 answered question46
 
skipped question
0
10. Some studies have concluded that SSRI drugs may increase the incidence of suicide and violence in pediatric, adolescent and young adult patients. Do you agree with that?
 Response
Percent
Response
Count
Yes
38.1%16
No
61.9%26
view commentOther (please specify)7
 answered question42
 
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4
11. Do you prescribe SSRI drugs to pediatric, adolescent and young adult patients?
 Response
Percent
Response
Count
Yes
65.9%29
No
34.1%15
view commentOther (please specify)4
 answered question44
 
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2
12. Do you like to participate in online healthcare surveys?
 Response
Percent
Response
Count
Yes
72.7%32
No
27.3%12
view commentOther (please specify)2
 answered question44
 
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2
13. Would you like to participate in other WhatDoctorsThink.com online surveys? You can see some other surveys we've performed at http://whatdoctorsthink.com/surveysamples.html
 Response
Percent
Response
Count
Yes
70.5%31
No
29.5%13
view commentOther (please specify)3
 answered question44
 
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2
14. Would you like to participate in various other types of online surveys where you receive honorariums for your time and expertise?
 Response
Percent
Response
Count
Yes
78.6%33
No
21.4%9
view commentOther (please specify)3
 answered question42
 
skipped question
4

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